Focal Interest
Focal Interest

Gut microbiota and health

External reference: https://openalex.org/T10066

  1. High-resolution spatial transcriptomics maps gut microbiome biogeography
    Spatial transcriptomics method combining enzymatic polyadenylation and RNA sequencing for high-resolution mapping of host-gut microbiome interactions and microbial biogeography.
  2. Maternal HIV linked to altered gut microbes and metabolites
    Longitudinal cohort analysis of gut dysbiosis and metabolomic alterations in mothers with HIV and their infants, identifying microbial and biochemical pathways linked to adverse perinatal outcomes.
  3. Gut microbiome is linked to colorectal cancer development and management
    Review of gut microbiome mechanisms in colorectal cancer carcinogenesis, examining pathogenic bacteria, protective functions, biomarker development, and therapeutic strategies.
  4. Baby-to-baby transmission shapes the infant gut microbiome
    Study reveals how baby-to-baby microbiome transmission in nurseries substantially shapes infant gut health during the first year, complementing maternal microbial inheritance.
  5. FMT with immunotherapy showed activity in NSCLC and melanoma
    Phase 2 trial: donor FMT plus first-line ICI in NSCLC and melanoma showed high ORRs and implicates loss of specific bacterial taxa in association with response.