What the study found
A cellulose-based sorbent called Cell-Azo was developed to support light-driven solid-phase extraction of amphetamine, with release triggered by UV light. The study reports that the material could reversibly switch its behavior through azobenzene's light-induced shape change.
Why the authors say this matters
The authors describe Cell-Azo as a potentially efficient, green, and controllable alternative for trace amphetamine analysis in complex samples. They suggest the light-controlled release is useful because it can disrupt binding sites without relying on dark desorption.
What the researchers tested
The researchers grafted azobenzene onto cellulose using atom-transfer radical polymerization. They verified the material with FT-IR, XPS, and UV-vis spectroscopy, then tested adsorption, light-responsive desorption, and a dispersive solid-phase extraction method coupled with HPLC-UV.
What worked and what didn't
The sorbent showed a maximum adsorption capacity of 19.86 mg·g^-1 at pH 9.0, with binding attributed to electrostatic interactions, π-π stacking, and hydrogen bonding. UV light produced 90.54% desorption efficiency, compared with less than 35% in the dark. The analytical method showed linearity from 0.05 to 2.00 mg·L^-1, an LOD of 7 μg·L^-1, an LOQ of 23.33 μg·L^-1, and precision with RSD below 5.1%; in spiked urine, recoveries were 69.53-75.68%.
What to keep in mind
The abstract does not describe broader limitations beyond the reported performance in spiked urine samples. The findings are presented for amphetamine analysis only, so the scope beyond this target analyte is not stated.
Key points
- Cell-Azo is a cellulose-based sorbent modified with azobenzene for light-driven amphetamine extraction.
- UV light triggered desorption efficiency of 90.54%, while desorption in the dark was below 35%.
- The maximum adsorption capacity was 19.86 mg·g^-1 at pH 9.0.
- The HPLC-UV method showed a linear range of 0.05-2.00 mg·L^-1 and an LOD of 7 μg·L^-1.
- Recoveries in spiked urine samples were 69.53-75.68%.
Disclosure
- Research title:
- Light-controlled cellulose sorbent enabled amphetamine extraction
- Publication date:
- 2026-02-27
- OpenAlex record:
- View
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