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Trifluoromethyl copper complexes were repurposed for saccharide difluoromethylation
Photo- and acid-mediated repurposing of Grushin's reagent enables efficient difluoromethylation of alcohols, saccharides, and bioactive molecules, generating antifungal leads.
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Metal-free trifluoromethylalkynylation of unsaturated peptides
Metal-free concurrent trifluoromethyl and alkynyl installation on unsaturated peptides under mild conditions, enabling rapid access to multifunctional peptide scaffolds for medicinal chemistry.
