Focal Interest
Focal Interest

Transcription factor

  1. DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
    Study reveals how elevated DNA damage and impaired repair mechanisms drive selective vulnerability of cortical neurons in MS and neuroinflammation.
  2. Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair
    Study reveals ATF4 regulates DNA repair genes critical for development of expanded upper cortical layers in mammalian brains, enabling progenitor survival under replicative stress.
  3. IDD5 and SDW3 link DELLA proteins to stem growth in cereals
    DELLA proteins interact with IDD5 and SDW3 transcription factors to regulate gibberellin-dependent stem elongation in wheat and barley, offering new breeding targets for cereal crop improvement.
  4. Three biomarkers were linked to angiogenesis and ISR in chondrosarcoma
    Multi-omics analysis identifies HSPA8, LMNA, and SERPINH1 as angiogenesis and integrated stress response biomarkers in chondrosarcoma with therapeutic potential.