Telomeres, Telomerase, and Senescence
External reference: https://openalex.org/T10937
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A Data-Analysis Pipeline for High-Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) in the Characterization of Telomeric Proteins
Development and validation of a bioinformatics pipeline for analyzing HT-SELEX data to characterize DNA-binding properties of telomeric proteins in human and C. elegans.
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Mitotic repair pathway drives chromoanasynthesis
Study reveals mitotic microhomology-mediated break-induced replication drives chromoanasynthesis, a complex chromosomal rearrangement mechanism in cancer and congenital disorders.
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C. elegans lifespan is limited by different competing causes of death
Study reveals how multiple age-related pathologies interact hierarchically to determine lifespan in C. elegans, showing bacterial infection and neoplasia mask or unmask each other's effects on.