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Functional groups strongly affect amino acid LC-MS derivatization
Systematic evaluation of derivatization agents for LC-MS amino acid analysis identifies isoquinoline-6-carboxylic acid NHS ester as optimal, achieving nanomolar sensitivity and long-term stability.
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Chemical recycling of hydrofluorocarbons by transfer fluorination
Chemical recycling method converts hydrofluorocarbons into usable fluoride sources through transfer fluorination, enabling synthesis of diverse fluorinated molecules at industrial scale.
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Modular synthesis of CF3/CHF2 dihydroquinoline sulfonyl fluorides
Modular synthesis of CF3/CHF2-substituted dihydroquinoline sulfonyl fluorides via [4+2] cycloaddition and sulfur(VI) fluoride exchange without transition metal catalysis.