Focal Interest
Focal Interest

Radical Photochemical Reactions

External reference: https://openalex.org/T10701

  1. Organocatalytic CDC adds fluoronitromethane to tetrahydroisoquinolines
    Organocatalytic cross-dehydrogenative coupling of tetrahydroisoquinolines with fluoronitromethane using Rose Bengal and green LED irradiation for sustainable fluorinated compound synthesis.
  2. Organophotoredox alkylation expands access to SF5-containing aliphatic molecules
    Metal-free organophotoredox catalysis enables efficient alkylation of vinylsulfur pentafluoride to synthesize SF5-containing aliphatic molecules under mild conditions with broad functional group.
  3. Photocatalysis enables synthesis of trifluoromethyl amidines and imidates
    Photocatalytic metal-free synthesis of α-trifluoromethyl amidines and imidates using isocyanides and trifluoroacetylsilanes, with mechanistic insights from DFT studies.
  4. Indoles converted to α-perfluoroalkylamino derivatives under mild conditions
    Novel sequential perfluoroalkylation and defluoroamination of indoles via sulfinate-derived radicals and HMDS-mediated C-F cleavage, yielding α-trifluoromethylated amines in up to 80% yield.
  5. Pentafluoroethylation of styrenes expanded by a sulfoximine reagent
    Synthesis and photocatalytic application of pentafluoroethyl sulfoximine for difunctionalization of styrenes via concurrent C-C and C-heteroatom bond formation under mild conditions.
  6. Photoredox method enables deoxytrifluoromethoxylation of phenols
    Photoredox-catalyzed deoxytrifluoromethoxylation installs OCF3 groups on phenols via in situ difluorophosgene generation and aryl carbonofluoridate activation.