Prospective cohort study

Explore tailored management strategies for familial hypercholesterolemia in pregnancy, addressing evidence gaps and the need for stage-specific, individualized approaches to optimize maternal and.

Rapid PCR testing on tongue swabs shows promise for tuberculosis diagnosis in sputum-scarce patients, with high specificity but limitations in detecting low bacillary loads.

Serum cyclophilin A concentrations are elevated in women with preeclampsia across pregnancy trimesters, with higher levels in early-onset disease, suggesting a role in pathogenesis.

Prospective randomized trial comparing flexible ureterorenoscopy and mini-percutaneous nephrolithotomy for pediatric renal pelvic stones under 2 cm with high density, showing comparable efficacy.

Urinary calcium-to-citrate ratio demonstrates moderate discriminatory power for kidney stone risk in infants and toddlers, with a threshold of 0.23 mg/mg indicating elevated lithogenic potential.

Nine-month all-oral TB regimens show 89.5% durable three-year cure rates but persistent linezolid neuropathy affects 22.6% of patients, raising safety concerns.

Nanopore-based targeted sequencing demonstrates 93% sensitivity and specificity for detecting Mycobacterium tuberculosis and drug resistance from non-sputum specimens in multicenter Chinese study.

Qualitative study examining women's experiences of general anesthesia conversion during cesarean delivery with inadequate neuraxial anesthesia and psychological outcomes.

Study evaluates reasoning-based large language models for predicting 12-week remission in depressive disorder patients undergoing antidepressant monotherapy.