Focal Interest
Focal Interest

Pathogenesis

  1. Cyclophilin A was higher before and during preeclampsia
    Serum cyclophilin A concentrations are elevated in women with preeclampsia across pregnancy trimesters, with higher levels in early-onset disease, suggesting a role in pathogenesis.
  2. Craniofacial fibrous dysplasia osteoblasts show altered bone homeostasis
    Study characterizes osteoblasts from craniofacial fibrous dysplasia, revealing elevated cAMP, impaired mineralization, and suppressed osteoclastogenesis contributing to abnormal bone homeostasis.