Organ Donation and Transplantation

External reference: https://openalex.org/T11163

  1. Donor ventilation time was not linked to 1-year lung function
    Evidence suggests prolonged donor mechanical ventilation does not impair recipient lung function after transplant, challenging traditional donor selection practices in lung transplantation.
  2. Care is central in anatomical pathology technologists’ autopsy work
    Qualitative study examining care practices among anatomical pathology technologists in medico-legal autopsies and implications for coronial justice legitimacy.
  3. Pediatric transplantation in China increased under new allocation rules
    Review of pediatric organ transplantation trends in China from 2015-2024, examining volumes, outcomes, regulatory frameworks, and challenges under reformed donation systems.
  4. Some medical drone payloads are classified as dangerous goods
    Analysis of dangerous goods compliance challenges for drone logistics in healthcare, finding 10% of medicines classified as hazardous and current procedures unscalable.
  5. Unconscious forces may shape assisted dying decisions
    Unconscious psychological forces shape assisted dying decisions. The authors propose integrating psychological assessment and clinician support to reduce bias and strengthen ethical safeguards.
  6. Donor TNFα linked to worse kidney graft outcomes
    High circulating tumor necrosis factor α in deceased organ donors associates with inferior kidney graft function and survival after transplantation through TNFR1-mediated injury mechanisms.
  7. Support provisions for donor conception vary across ten countries
    Comparative analysis of donor conception contexts and psychosocial support provisions across ten Western jurisdictions, examining gaps in counselling and services for all stakeholders.
  8. Ethical tensions surround CPR in brain-dead pediatric organ donors
    Ethics analysis of organ-preserving CPR in pediatric brain-dead patients, examining tensions between organ viability, bodily dignity, and institutional coordination.
  9. Standardizing donation after circulatory death organ recovery
    Viewpoint on standardizing organ procurement practices, particularly normothermic regional perfusion, for donation after circulatory death transplantation.
  10. Donor acceptance patterns in pancreas transplant changed over time
    Population cohort study reveals declining DCD pancreas utilization despite good outcomes, while Hepatitis C and IVDU donors gain acceptance in transplantation practice.
  11. Donor age affects younger liver transplant recipients more
    Donor age disproportionately impacts younger liver transplant recipients while older recipients tolerate older grafts well. Study provides age-based thresholds for optimized donor-recipient matching.
  12. SIPAT evaluation highlights alcohol use and education
    Domain-level SIPAT assessment reveals alcohol use and lower education as primary psychosocial vulnerabilities across transplant candidates, supporting targeted pre-transplant evaluation.
  13. Familist incentives may promote deceased organ donation in Islamic regions
    Essay examining familist incentive adoption for deceased organ donation in Islamic regions, analyzing alignment with classical Islamic moral frameworks and practical implementation strategies.
  14. Psychological interventions may improve transplant-related well-being
    Systematic review commentary on psychological interventions in organ transplantation, examining placebo and nocebo effects as overlooked explanatory mechanisms for clinical outcomes.
  15. Brain Death and Organ Donation in Romania: A Nationwide Survey of Intensivists’ Perceptions and Clinical Practices
    Romanian intensivists' survey reveals barriers to organ donation including communication gaps, insufficient training, and low institutional prioritization of procurement processes.
  16. MuST AKT was feasible and acceptable in a pilot trial
    MuST AKT pilot trial tests structured intervention to increase living donor kidney transplants through multidisciplinary support and social network engagement.
  17. Wait time policy increased transplant rates for Black candidates
    Quasi-experimental evaluation of wait time modification policy effects on Black kidney transplant candidates, addressing race-based kidney function estimation bias in allocation algorithms.
  18. dd-cfDNA tracks kidney rejection activity across the continuum
    Donor-derived cell-free DNA quantifies kidney allograft rejection non-invasively across histopathological spectra, with combined scoring optimizing detection of microvascular and antibody-mediated.
  19. Commentary supports respiratory therapist-led donor lung management
    Commentary advocating respiratory therapist-led, EIT-guided precision ventilation for donor lung protection and allograft viability optimization during procurement management.
  20. Review of psychosocial challenges in transplantation
    Review of psychosocial challenges in transplantation with emphasis on lung-specific studies, guidelines, and research gaps for clinical practice.