Focal Interest
Focal Interest

Nucleophile

  1. Photocatalysis enables synthesis of trifluoromethyl amidines and imidates
    Photocatalytic metal-free synthesis of α-trifluoromethyl amidines and imidates using isocyanides and trifluoroacetylsilanes, with mechanistic insights from DFT studies.
  2. Sunlight-driven photocatalyst cleaves PFAS carbon–fluorine bonds
    Z-scheme photocatalyst CuInS2/BiOCl composite enables visible-light-driven degradation of PFAS through directed charge transfer, achieving 96% removal in sunlight-driven continuous-flow systems.
  3. Modular synthesis of CF3/CHF2 dihydroquinoline sulfonyl fluorides
    Modular synthesis of CF3/CHF2-substituted dihydroquinoline sulfonyl fluorides via [4+2] cycloaddition and sulfur(VI) fluoride exchange without transition metal catalysis.
  4. Thiolate-mediated cyclization yields 2-quinolones efficiently
    Thiolate-mediated cyclization protocol for synthesis of 2-quinolones and 2-aza-quinolones from aminocinnamic acid derivatives with broad substrate scope and gram-scale scalability.
  5. Phenanthrenone-derived ketone is more electrophilic than acenaphthenone-derived ketone
    Kinetic and computational quantification of electrophilicity for phenanthrenone‑ and acenaphthenone‑derived α,β‑unsaturated ketones: Mayr E parameters, transition‑state analysis, and.