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DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
Study reveals how elevated DNA damage and impaired repair mechanisms drive selective vulnerability of cortical neurons in MS and neuroinflammation.
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Parieto-frontal communication supports accurate quantity judgments in primates
Study reveals that coordinated communication between parietal and frontal brain regions enables accurate numerical judgments in macaques, with disrupted interaction causing errors.
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Neuronal alpha-synuclein clearance is impaired and transfer to microglia increases
Neurons with impaired α-synuclein clearance transfer aggregates to microglia via tunneling nanotubes. Study reveals dysfunctional neuronal autophagy drives intercellular aggregate transfer and.