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DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
Study reveals how elevated DNA damage and impaired repair mechanisms drive selective vulnerability of cortical neurons in MS and neuroinflammation.
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Neurodegeneration, Oxidative Stress, NGF/TrkA/P75NTR, and PGE2 Dysregulation Induced by PFOS Single and Repeated Treatment: Partial Protection by T3 and Other Therapeutic Approaches
PFOS induces neurodegeneration in basal forebrain cholinergic neurons through oxidative stress, PGE2 dysregulation, and NGF pathway disruption; T3 treatment offers partial neuroprotection.