Focal Interest
Focal Interest

Molecular Biology Techniques and Applications

External reference: https://openalex.org/T11970

  1. Shotgun DNA sequencing evidence: Sample-specific and unknown genotyping error probabilities
    Extension of the wgsLR statistical model for shotgun DNA sequencing in forensics, accommodating asymmetric and unknown genotyping error probabilities through profile likelihood and Bayesian methods.
  2. hsa-miR-96-5p validated as a reference for vitreous humor PMI estimation
    Validation of hsa-miR-96-5p as a stable endogenous reference gene for qPCR-based post-mortem interval estimation in vitreous humor forensic analysis.
  3. SNP profile completeness varied, but DNA metrics only partly predicted it
    Large-scale analysis of DNA quantification metrics and SNP sequencing performance in unidentified human remains shows robust applicability for forensic identification despite moderate predictability.