Focal Interest
Focal Interest

Metabolomics

  1. F6H8 altered human liver cell metabolism and produced a PFAS-like metabolite
    F6H8, an ophthalmic treatment for dry eye, produces PFAS-like metabolites and triggers broad metabolic disruption in human hepatocytes, raising long-term safety concerns.
  2. Targeted Metabolomic Profiling of Carnitines Reveals Diagnostic Candidates in Postpartum Cardiomyopathy
    Targeted metabolomics study identifies altered carnitine profiles in postpartum cardiomyopathy, with acetylcarnitine and related species as potential diagnostic biomarker candidates.
  3. Barley metabolite levels varied with genotype and stress type
    Metabolomic characterization of barley stress responses reveals genotype-dependent metabolite accumulation patterns and candidate biomarkers under single and combined abiotic stresses.
  4. Microbial metabolite linked to epithelial damage in EAE mice
    Multi-omics study reveals how the microbial metabolite phenyllactic acid drives mitochondrial dysfunction and intestinal barrier damage in experimental autoimmune encephalomyelitis through OXPHOS.
  5. Urine metabolomics showed distinct patterns across paediatric TB states
    Urine metabolomics via NMR spectroscopy shows promise for early diagnosis of paediatric tuberculosis, achieving 97% accuracy in distinguishing active TB from latent infection.