Focal Interest
Focal Interest

Metabolite

  1. F6H8 altered human liver cell metabolism and produced a PFAS-like metabolite
    F6H8, an ophthalmic treatment for dry eye, produces PFAS-like metabolites and triggers broad metabolic disruption in human hepatocytes, raising long-term safety concerns.
  2. Urolithin A may act on obesity and metabolic dysfunction through multiple pathways
    Urolithin A, a gut microbiota metabolite from ellagitannins, shows multi-target potential for obesity and metabolic dysfunction through thermogenesis activation, lipid metabolism regulation, and.
  3. Microbial metabolite linked to epithelial damage in EAE mice
    Multi-omics study reveals how the microbial metabolite phenyllactic acid drives mitochondrial dysfunction and intestinal barrier damage in experimental autoimmune encephalomyelitis through OXPHOS.