Focal Interest
Focal Interest

Inflammation

  1. Gut microbiota changes linked to less atherosclerosis in mice
    Panax ginseng and Polygonum cuspidatum reduce atherosclerosis in mice by modulating gut microbiota composition and metabolite profiles, offering mechanistic insights for cardiovascular disease.
  2. Donor TNFα linked to worse kidney graft outcomes
    High circulating tumor necrosis factor α in deceased organ donors associates with inferior kidney graft function and survival after transplantation through TNFR1-mediated injury mechanisms.
  3. Gut-brain signaling dysfunction is linked to age-related memory decline
    Age-associated cognitive decline driven by impaired gut-brain interoceptive signalling through microbial metabolite-induced vagal dysfunction and hippocampal neuronal dysfunction.
  4. dd-cfDNA tracks kidney rejection activity across the continuum
    Donor-derived cell-free DNA quantifies kidney allograft rejection non-invasively across histopathological spectra, with combined scoring optimizing detection of microvascular and antibody-mediated.