Infectious Diseases and Tuberculosis

External reference: https://openalex.org/T11381

  1. Pediatric intracranial abscesses often required varied treatment and molecular testing improved diagnosis
    Pediatric intracranial abscess management analysis reveals molecular testing improves diagnosis; structural sequelae are common but prognostically unclear.
  2. Tuberculous peritonitis mimicked encapsulating peritoneal sclerosis
    Case report of tuberculous peritonitis mimicking encapsulating peritoneal sclerosis in a peritoneal dialysis patient, diagnosed by metagenomic sequencing.
  3. Review outlines imaging roles in spinal tuberculosis
    A comprehensive review of imaging modalities for spinal tuberculosis diagnosis and monitoring, emphasizing MRI as gold standard and emerging techniques for characterization.
  4. Tongue swab PCR showed high accuracy for pulmonary tuberculosis
    Rapid PCR testing on tongue swabs shows promise for tuberculosis diagnosis in sputum-scarce patients, with high specificity but limitations in detecting low bacillary loads.
  5. Short-course anti-TB therapy followed regression of reactivated focus
    Case report of ICI-induced TB reactivation managed with short-course anti-TB therapy followed by continued checkpoint inhibitor monotherapy, suggesting personalized management alternatives to.
  6. Isoniazid monoresistance and alopecia occurred together in one TB case
    Severe alopecia developed in a 22-year-old woman with isoniazid-monoresistant tuberculosis after starting treatment. Hair regrowth occurred after discontinuing isoniazid, highlighting the.
  7. Atrophic arm plaques were linked to Mycobacterium abscessus infection
    Atypical mycobacterial infection in adolescent presenting with atrophic plaques and concurrent epidermal inclusion cyst. Case report highlights diagnosis and antibiotic resistance considerations.
  8. MRI scores rapidly differentiate pyogenic and tuberculous spondylitis
    MRI-based scoring systems rapidly differentiate pyogenic from tuberculous spondylitis, reducing inappropriate antibiotic therapy and improving clinical decision-making in spinal infections.
  9. About half with trace ultra results were recommended tuberculosis therapy
    Study of 311 adults with trace-positive TB tests shows 20% culture-confirmed disease at enrollment and identifies clinical predictors to guide treatment decisions in settings with uncertain TB status.
  10. Patient delay in tuberculosis care increased in Shenyang from 2015 to 2024
    Study of 38,928 TB patients in Shenyang reveals 56.65% experience consultation delays. Female, elderly, ethnic minority, and farmer patients at highest risk. Targeted interventions needed.
  11. Compensatory mutations showed limited effect on MDR/RR-TB clustering
    Population-based whole-genome sequencing study of 206 MDR/RR-TB isolates in China reveals compensatory mutations have limited impact on transmission clustering.
  12. Thwaites and Marais scores are suggested as first-line TBM screening tests
    Systematic review of 21 tuberculous meningitis diagnostic scoring systems, identifying 4 with external validation and recommending Thwaites and Marais scores as first-line screening tools.
  13. Seroprevalence of mycobacteria detected in Korean swine
    Nationwide Korean seroprevalence survey of Mycobacterium bovis and avium in domestic sows and wild boars, revealing 4.54-5.91% M. bovis and 7.71-10.10% M. avium exposure.
  14. CBC-derived ratios have limited diagnostic value in rheumatic disease tuberculosis
    Explore CBC-derived ratios for tuberculosis diagnosis in rheumatic disease patients. Study shows limited standalone accuracy but potential as adjunctive screening tools alongside microbiological.
  15. Rare hip infection presented as a giant pseudotumor
    First documented periprosthetic joint infection with pseudotumor formation caused by Granulicatella adiacens, identified via advanced diagnostics and managed with multimodal surgical intervention.
  16. Nine-month oral TB regimens showed durable three-year outcomes
    Nine-month all-oral TB regimens show 89.5% durable three-year cure rates but persistent linezolid neuropathy affects 22.6% of patients, raising safety concerns.
  17. tNGS accurately detected tuberculosis and drug resistance in non-sputum samples
    Nanopore-based targeted sequencing demonstrates 93% sensitivity and specificity for detecting Mycobacterium tuberculosis and drug resistance from non-sputum specimens in multicenter Chinese study.
  18. TMP/SMX use was linked to fewer severe infections in IIM
    Trimethoprim-sulfamethoxazole reduces severe infection risk in idiopathic inflammatory myopathy patients receiving immunosuppressive therapy, with significant protection against respiratory tract.
  19. Urine metabolomics showed distinct patterns across paediatric TB states
    Urine metabolomics via NMR spectroscopy shows promise for early diagnosis of paediatric tuberculosis, achieving 97% accuracy in distinguishing active TB from latent infection.
  20. Do we need to revise the dose of isoniazid for the treatment of tuberculosis in children?
    Pediatric tuberculosis challenges including diagnostic barriers, treatment access gaps, and integration of WHO evidence-based algorithms and clinical standards for improved child and adolescent care.