Focal Interest
Focal Interest

Gut flora

  1. Gut microbiota changes linked to less atherosclerosis in mice
    Panax ginseng and Polygonum cuspidatum reduce atherosclerosis in mice by modulating gut microbiota composition and metabolite profiles, offering mechanistic insights for cardiovascular disease.
  2. Gut microbiome helps shape Parkinson’s drug interactions
    Drug-microbiome-drug interaction study reveals how COMT inhibitors used with levodopa alter gut bacteria and affect medication metabolism in Parkinson's patients.
  3. Urolithin A may act on obesity and metabolic dysfunction through multiple pathways
    Urolithin A, a gut microbiota metabolite from ellagitannins, shows multi-target potential for obesity and metabolic dysfunction through thermogenesis activation, lipid metabolism regulation, and.
  4. Fermentation changes polyphenols into more bioactive metabolites
    Review examining how microbial fermentation converts plant polyphenols into bioavailable metabolites that enhance gut health and systemic immune function through selective microbiota modulation.
  5. Gut microbiota metabolic reprogramming may drive metabolic disease
    Dysbiosis-induced microbial metabolic reprogramming drives metabolic disease through alterations in lipid, glucose, amino acid, and uric acid metabolism.
  6. Antibiotic use was linked to long-lasting gut microbiome changes
    Population-based study linking 8-year antibiotic prescription data with fecal metagenomes in 14,979 adults to characterize associations between oral antibiotic use and gut microbiome composition.
  7. Ecological network balance index distinguishes healthy and dysbiotic gut states
    Ecological network balance index quantifies positive and negative microbial interactions as a marker of dysbiosis, differentiating health from disease states with mechanistic grounding.
  8. Maternal microbiota affects pregnancy outcomes and infant immune development
    How maternal and infant gut microbiomes shape pregnancy outcomes, immune development, and long-term health during the critical first 1000 days of life.
  9. Gut microbiota shifts and possible markers linked to postoperative enterocolitis
    Longitudinal study identifies distinct gut microbiota alterations in Hirschsprung disease patients, revealing bacterial markers for postoperative enterocolitis risk.
  10. Maternal HIV linked to altered gut microbes and metabolites
    Longitudinal cohort analysis of gut dysbiosis and metabolomic alterations in mothers with HIV and their infants, identifying microbial and biochemical pathways linked to adverse perinatal outcomes.
  11. Gut microbiome is linked to colorectal cancer development and management
    Review of gut microbiome mechanisms in colorectal cancer carcinogenesis, examining pathogenic bacteria, protective functions, biomarker development, and therapeutic strategies.