Focal Interest
Focal Interest

Genomics, phytochemicals, and oxidative stress

External reference: https://openalex.org/T11332

  1. Polyphenols show both beneficial and harmful dose-dependent effects
    Review examines the paradoxical bioactivity of polyphenols: beneficial antioxidant effects at dietary levels versus pro-oxidant toxicity, carcinogenicity, and organ damage at high supplemental doses.
  2. Plant polyphenols are linked to antioxidant and anti-inflammatory mechanisms
    Evidence synthesis on polyphenol antioxidant mechanisms, redox signaling, and bioavailability constraints across disease contexts, emphasizing dose realism and microbiota variability.