Genetic Associations and Epidemiology

PALM, a quasi-Poisson regression framework, enables fast and reliable association discovery in large-scale microbiome studies by controlling false discovery rates and improving power.

Benchmark evaluation of ancient DNA genetic relatedness estimation methods reveals multiple sources of bias and limitations in current approaches.

Extension of the wgsLR statistical model for shotgun DNA sequencing in forensics, accommodating asymmetric and unknown genotyping error probabilities through profile likelihood and Bayesian methods.

Study finds common variants in extended genomic regions, not rare variants, explain most unexplained admixture mapping signals in Hispanic/Latino populations.