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Organophotoredox alkylation expands access to SF5-containing aliphatic molecules
Metal-free organophotoredox catalysis enables efficient alkylation of vinylsulfur pentafluoride to synthesize SF5-containing aliphatic molecules under mild conditions with broad functional group.
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Photocatalysis enables synthesis of trifluoromethyl amidines and imidates
Photocatalytic metal-free synthesis of α-trifluoromethyl amidines and imidates using isocyanides and trifluoroacetylsilanes, with mechanistic insights from DFT studies.
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Indoles converted to α-perfluoroalkylamino derivatives under mild conditions
Novel sequential perfluoroalkylation and defluoroamination of indoles via sulfinate-derived radicals and HMDS-mediated C-F cleavage, yielding α-trifluoromethylated amines in up to 80% yield.
