Focal Interest
Focal Interest

Extracellular

  1. F6H8 altered human liver cell metabolism and produced a PFAS-like metabolite
    F6H8, an ophthalmic treatment for dry eye, produces PFAS-like metabolites and triggers broad metabolic disruption in human hepatocytes, raising long-term safety concerns.
  2. PstCFEM2 promotes wheat susceptibility by activating TaHA2
    Pst stripe rust effector PstCFEM2 activates wheat H+-ATPase TaHA2, promoting apoplastic acidification that suppresses immunity. CRISPR knockout of TaHA2 confers durable rust resistance.
  3. EV-delivered miR-181a-3p may protect degenerating retinal ganglion cells
    Extracellular vesicles deliver miR-181a-3p to protect degenerating retinal ganglion cells, offering a novel therapeutic approach for glaucoma and optic neuropathies through biocompatible gene.