Focal Interest
Focal Interest

DNA sequencing

  1. A Data-Analysis Pipeline for High-Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) in the Characterization of Telomeric Proteins
    Development and validation of a bioinformatics pipeline for analyzing HT-SELEX data to characterize DNA-binding properties of telomeric proteins in human and C. elegans.
  2. Genomic factors linked to tandem repeat mutability
    Study reveals genomic factors shaping tandem repeat mutagenesis using long-read sequencing across a four-generation pedigree, identifying associations with TR length, motif composition, and.
  3. Shotgun DNA sequencing evidence: Sample-specific and unknown genotyping error probabilities
    Extension of the wgsLR statistical model for shotgun DNA sequencing in forensics, accommodating asymmetric and unknown genotyping error probabilities through profile likelihood and Bayesian methods.
  4. SNP profile completeness varied, but DNA metrics only partly predicted it
    Large-scale analysis of DNA quantification metrics and SNP sequencing performance in unidentified human remains shows robust applicability for forensic identification despite moderate predictability.