Disease

Latent profile analysis identified three distinct depressive symptom patterns in Korean adults during COVID-19, with interpersonal conflicts and younger age predicting severe profiles.

Discrete choice experiment reveals that people with advanced Parkinson's disease prioritize treatment efficacy and route of administration when selecting therapies.

Drug-microbiome-drug interaction study reveals how COMT inhibitors used with levodopa alter gut bacteria and affect medication metabolism in Parkinson's patients.

Review of current fetal cardiac intervention practices and challenges, examining intervention timing, patient selection criteria, and complication management in severe congenital heart disease.

Molecular imaging reveals late-life depression involves altered neurotransmitter systems, Alzheimer's pathology, and neuroinflammation, supporting development of targeted mechanism-based treatments.

Ethical case for longevity science grounded in autonomy and self-ownership rather than consequences alone; addresses philosophical and societal objections to aging research.

Online health education delivered during prenatal care significantly improves COVID-19 knowledge and reduces pregnancy anxiety in first-time pregnant women during the post-pandemic period.

Placental abruption in twin pregnancies associates with elevated cardiovascular disease risk in offspring, with preterm delivery mediating substantial but incomplete effects.

Environmental stressors and air pollution linked to respiratory morbidity in older adults in Slovenia. Study of 4,870 emergency department visits examines associations with meteorological.

Dysbiosis-induced microbial metabolic reprogramming drives metabolic disease through alterations in lipid, glucose, amino acid, and uric acid metabolism.

Ecological network balance index quantifies positive and negative microbial interactions as a marker of dysbiosis, differentiating health from disease states with mechanistic grounding.

How maternal and infant gut microbiomes shape pregnancy outcomes, immune development, and long-term health during the critical first 1000 days of life.

Single-case study examining Quranic-based psychotherapy for major depressive disorder in a 60-year-old woman, showing sustained symptom reduction through follow-up.

Review synthesizes big data and machine learning integration in U.S. infectious disease surveillance, examining data sources and computational methods for detection, forecasting, and control.

Mathematical modeling frameworks for infectious disease dynamics integrate computational methods, network analysis, and machine learning to forecast epidemics and optimize public health interventions.

Machine learning analysis of one million canine electronic health records identifies disease phenotypes, breed predispositions, and emerging health patterns using unsupervised topic modeling.

Cross-sectional study of 127 PAD patients examining associations between dietary habits, physical activity, and SF-36 quality-of-life domains using standardized instruments.

Longitudinal study identifies distinct gut microbiota alterations in Hirschsprung disease patients, revealing bacterial markers for postoperative enterocolitis risk.

Qualitative study of 40 Long COVID patients identifies key stressors including fatigue, cognitive impairment, and social isolation, revealing diverse emotion and problem-oriented coping strategies.

Review examines COPD burden in Sub-Saharan Africa and barriers to implementing long-term oxygen therapy, providing recommendations for policy and healthcare strategies.