Cytosol
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PstCFEM2 promotes wheat susceptibility by activating TaHA2
Pst stripe rust effector PstCFEM2 activates wheat H+-ATPase TaHA2, promoting apoplastic acidification that suppresses immunity. CRISPR knockout of TaHA2 confers durable rust resistance.
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Cryo-EM shows multiple cytochrome P450 reductase conformations
3.3 Å cryo-EM of full-length rat cytochrome P450 reductase reveals a relaxed compact state, additional compact variants, and ~20% of particles with displaced or missing FMN domain.

