Focal Interest
Focal Interest

Conjugate

  1. Oxoammonium catalysis enables enantioselective desymmetrization of meso-pyrrolidines
    Oxoammonium-catalyzed desymmetrization of meso-pyrrolidines via enantioselective hydride transfer with over 90% ee, featuring mechanistic insights from isolated intermediates.
  2. Thiolate-mediated cyclization yields 2-quinolones efficiently
    Thiolate-mediated cyclization protocol for synthesis of 2-quinolones and 2-aza-quinolones from aminocinnamic acid derivatives with broad substrate scope and gram-scale scalability.