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Effort boosts dopamine release through acetylcholine
Effort amplifies dopamine reward responses through acetylcholine modulation of dopamine axons in the nucleus accumbens, explaining how organisms maintain reward-seeking under resource constraints.
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Neurodegeneration, Oxidative Stress, NGF/TrkA/P75NTR, and PGE2 Dysregulation Induced by PFOS Single and Repeated Treatment: Partial Protection by T3 and Other Therapeutic Approaches
PFOS induces neurodegeneration in basal forebrain cholinergic neurons through oxidative stress, PGE2 dysregulation, and NGF pathway disruption; T3 treatment offers partial neuroprotection.