Focal Interest
Focal Interest

Chemical Synthesis and Analysis

External reference: https://openalex.org/T10911

  1. Modular synthesis of CF3/CHF2 dihydroquinoline sulfonyl fluorides
    Modular synthesis of CF3/CHF2-substituted dihydroquinoline sulfonyl fluorides via [4+2] cycloaddition and sulfur(VI) fluoride exchange without transition metal catalysis.
  2. Metal-free trifluoromethylalkynylation of unsaturated peptides
    Metal-free concurrent trifluoromethyl and alkynyl installation on unsaturated peptides under mild conditions, enabling rapid access to multifunctional peptide scaffolds for medicinal chemistry.