Focal Interest
Focal Interest

Cancer

  1. Talazoparib resistance in triple-negative breast cancer linked to BRN2 and SHLD2
    Study identifies BRN2-mediated and SHLD2-related resistance to talazoparib in BRCA-mutant breast cancer, proposing combination therapy approaches to improve neoadjuvant treatment outcomes.
  2. U.S. cancer mortality declines varied by county income and location
    County-level analysis reveals disparities in cancer mortality decline across geography, income, and urbanization in the United States.
  3. Robotic process automation improved cancer registry abstraction efficiency
    RPA implementation for cancer registry data abstraction achieved 74% time reduction in gastric cancer and 30% in breast cancer, with success dependent on clinician cooperation and output monitoring.
  4. Ukraine’s cancer care largely recovered after wartime disruption
    Study examines Ukrainian oncology system's resilience during Russian invasion, documenting rapid recovery mechanisms, international partnerships and persistent barriers to equitable care access.
  5. Designing Care-fully: Robots for Acute Cancer Care
    Care ethics framework for designing social robots in acute cancer care, examining how robots can amplify compassion in emergency department settings through collaborative stakeholder research.
  6. Hypodermoclysis appears generally safe in advanced cancer
    Hypodermoclysis shows favorable safety and feasibility for hydration in advanced cancer patients receiving palliative care, with mild complications in 17% of cases and no consistent survival benefits.
  7. PFOA-linked bladder cancer signals identified in transcriptomic analysis
    Study reveals molecular mechanisms linking PFOA exposure to bladder cancer through integrative toxicogenomics and gene expression analysis, identifying key transcriptional signatures for cancer.