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Talazoparib resistance in triple-negative breast cancer linked to BRN2 and SHLD2
Study identifies BRN2-mediated and SHLD2-related resistance to talazoparib in BRCA-mutant breast cancer, proposing combination therapy approaches to improve neoadjuvant treatment outcomes.
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Robotic process automation improved cancer registry abstraction efficiency
RPA implementation for cancer registry data abstraction achieved 74% time reduction in gastric cancer and 30% in breast cancer, with success dependent on clinician cooperation and output monitoring.