Focal Interest
Focal Interest

Bone Tumor Diagnosis and Treatments

External reference: https://openalex.org/T10975

  1. Infraorbital swelling revealed rare extramedullary myeloma relapse
    Case report of infraorbital swelling caused by extramedullary multiple myeloma, highlighting the importance of considering plasma cell neoplasms in facial mass differential diagnosis.
  2. Synovial chondromatosis caused external auditory canal stenosis
    First documented case of synovial chondromatosis causing external auditory canal stenosis with atypical inferior joint space involvement treated via combined open and endoscopic surgery.
  3. Craniofacial osteomas were most often found in the frontal bone
    Study establishes diagnostic and treatment protocols for craniofacial osteomas in 141 patients, showing frontal bone predominance, female predominance, and no recurrences with surgical management.
  4. Periocular collagenous fibroma with bone formation described
    Rare benign periocular collagenous fibroma with metaplastic ossification mimics aggressive lesions. Case study shows MRI findings, histopathology, and complete excision with no recurrence.
  5. Olutasidenib showed disease control in IDH1-mutated chondrosarcoma
    Phase 1b/2 trial of olutasidenib in IDH1-mutated chondrosarcoma shows disease control without dose-limiting toxicities; 52% stable disease rate in recurrent/metastatic disease.
  6. Combination therapy showed a temporary response in metastatic DDCS
    Case report demonstrates promising response to pembrolizumab and pazopanib combination therapy in metastatic dedifferentiated chondrosarcoma, highlighting emerging systemic treatment options.
  7. Correlation Between Molecular Genetic Analysis and Nuclear Pleomorphism in Long-Term Recurrent and Metastatic Chordoma
    Quantitative nuclear morphometry combined with genetic analysis reveals morphological markers of recurrence risk in chordoma, offering potential for improved prognostic assessment.
  8. Successful Surgical Treatment of Pediatric FUS :: TFCP2 -Positive Rhabdomyosarcoma of the Mandible: A Case Report
    Surgical resection of chemoresistant FUS::TFCP2-positive rhabdomyosarcoma in an 11-year-old with mandibular tumor. Case report demonstrates radical surgery success after failed chemotherapy.
  9. Childhood mandibular myxoma presented with persistent trismus
    Case report of odontogenic myxoma in a 5-year-old presenting with trismus, demonstrating persistent functional impairment despite successful tumor removal and bone regeneration.
  10. Pediatric maxillary mesenchymal chondrosarcoma with HEY1::NCOA2 fusion
    Case report of mesenchymal chondrosarcoma in a 13-year-old with HEY1::NCOA2 fusion treated with multimodal therapy including sirolimus targeting mTOR pathway.
  11. Rare cervical spinal osteochondroma in a child with hereditary exostoses
    Case report of rare osteochondroma in the C5 spinous process of a 7-year-old with hereditary exostoses, emphasizing diagnostic imaging and clinical significance of spinal involvement.
  12. Rare myoepithelial tumor with EWSR1-PBX3 fusion in rib and soft tissue
    Myoepithelial tumor with EWSR1-PBX3 fusion in rib and soft tissue: molecular and clinicopathological findings with disease-free outcome.
  13. Delayed diagnosis of thoracic spinal tumor led to paraplegia
    Case study of delayed diagnosis of giant thoracic meningioma in resource-limited setting, revealing diagnostic challenges, management strategies, and systemic barriers to timely neurosurgical.
  14. Combined reconstruction preserved forearm mechanics after distal radius resection
    Integrated reconstruction of distal radius following oncologic resection using proximal fibular autograft and distal oblique bundle reconstruction preserves forearm mechanics.
  15. Rare solitary fibrous tumor found in the floor of the mouth
    Case report of solitary fibrous tumor of the oral floor in a 42-year-old male, confirmed via histopathology and STAT6 immunohistochemistry; highlights rare intraoral presentation.
  16. En bloc resection showed strong control and recovery in proximal fibular GCT
    En bloc resection of proximal fibular giant cell tumours in young patients achieves 85% complete nerve recovery with no recurrence and excellent knee stability outcomes at one-year follow-up.
  17. Deep learning improved classification of jaw fibro-osseous lesions
    Deep learning model using ResNet-50 classifies fibro-osseous jaw lesions from histology images with 86% accuracy, outperforming pathologists in differentiating fibrous dysplasia, cemento-ossifying.
  18. Craniofacial fibrous dysplasia osteoblasts show altered bone homeostasis
    Study characterizes osteoblasts from craniofacial fibrous dysplasia, revealing elevated cAMP, impaired mineralization, and suppressed osteoclastogenesis contributing to abnormal bone homeostasis.
  19. Anchor reattachment supported knee stability after proximal fibula tumor resection
    Surgical techniques for proximal fibular tumor resection with nerve preservation and tibial reconstruction to maintain knee stability and function.
  20. Middle lobe torsion was diagnosed early after right upper lobectomy
    Middle lobe torsion after upper lobectomy: rare postoperative complication requiring diagnostic imaging, bronchoscopy, and specialized anesthetic management with double-lumen intubation and.