Focal Interest
Focal Interest

Biotransformation

  1. F6H8 altered human liver cell metabolism and produced a PFAS-like metabolite
    F6H8, an ophthalmic treatment for dry eye, produces PFAS-like metabolites and triggers broad metabolic disruption in human hepatocytes, raising long-term safety concerns.
  2. Fermentation changes polyphenols into more bioactive metabolites
    Review examining how microbial fermentation converts plant polyphenols into bioavailable metabolites that enhance gut health and systemic immune function through selective microbiota modulation.