Focal Interest
Focal Interest

Asymmetric induction

  1. Oxoammonium catalysis enables enantioselective desymmetrization of meso-pyrrolidines
    Oxoammonium-catalyzed desymmetrization of meso-pyrrolidines via enantioselective hydride transfer with over 90% ee, featuring mechanistic insights from isolated intermediates.
  2. Chiral carbon-bonding donors showed asymmetric induction
    Carbon-bonding donors induce asymmetric induction via noncovalent interaction, demonstrated through oxa-Pictet-Spengler cyclization with oxocarbenium intermediates.